A study of hepatoprotective activity of hedyotis corymbosa. Isolation of an anticancer asperuloside from hedyotis. Hedyotis diffusa induces apoptosis in human breast cancer cells and also inhibits tumor angiogenesis 2628. Materials hedyotis corymbosa samples were collected from indonesian medicinal and aromatic crops research institute. The plants database includes the following 1 subspecies of oldenlandia corymbosa. Integrated taxonomic information system hepo10 wildlife. Files are available under licenses specified on their description page. Methanolic extracts of these two plants were tested in vitro on choloroquine sensitive mrcpf20 and resistant mrcpf303 strains. Pdf objective hedyotis corymbosa shui xian cao, hc is the main antitumor medicine in china and other southeast asian countries. Kinetic studies for ultrasoundassisted supercritical carbon dioxide extraction of triterpenic acids from healthy tea ingredient hedyotis diffusa and hedyotis corymbosa.
Molecules free fulltext the hedyotis diffusa willd. Min wang, zhumei shi, dan liu, gongyu zhang, jiahao sha, binghua jiang. Widely differing treatments have long been used in different regions and floras. List of various diseases cured by hedyotis diffusa. It has long been used traditionally as an antiinflammatory diuretics, antipyretic, and antitoxin and enhances phagocytosis white. Uses, benefits, cures, side effects, nutrients in hedyotis herbacea. Up to now, 171 compounds have been reported from h. Click below on a thumbnail map or name for subspecies profiles. This plant is used for their medicinal properties as a folk medicine to treat jaundice, mouth wash in toothache. Antidepressant effect of hedyotis corymbosa extract in. According to kusuma and zaky 2, the whole plant of pearl grass can be used as medicine.
The aim of this research is to know the distribution profile of asperuloside, scandosidmethylesther, at the leaf, stem, fruit, and root of hedyotis corymbosa l. On the other hand, pearl grass hedyotis corymbosa l. This confusion has led to a growing concern about their identification and quality evaluation. Herbal extracts of andrographis paniculata ap and hedyotis corymbosa hc are known as hepatoprotective and feverreducing drugs since ancient time and they have been used regularly by the people in the south asian subcontinent. It is also an important component in several ayurvedic formulations and. Hedyotis corymbosa linn is spreading, suffruticose annual, belongs to family rubiaceae frequently met with in field through out india, usually during rainy season. Antihepatotoxic potential of hedyotis corymbosa against d. Hedyotis is a very problematic genus or group of genera. Source large mammals small mammals water birds terrestrial birds. Please note that this is a trial program and may end. Neither the overall identity and limits of this lineage, nor the evolutionary patterns within it, are at all understood or delineated. Bai hua she she cao hedyotis best chinese medicines. How hedyotis diffusa is effective for various diseases is listed in repertory format. Hedyotis diffusa combined with scutellaria barbata are the.
The genus hedyotis family of rubiaceae are mainly distributed in the tropical and subtropical region of the world. And chemical constituents of hedyotis capitellata by rohaya ahmad february 2005 chairman. Names of hedyotis diffusa in various languages of the world are also given. This means inflammation and infection of many kinds. The hepatoprotective activity was assessed using various biochemical. Oldenlandia coymbosa, a flowering plant figure 1,2 in the family rubiaceae, commonly called diamond flower is an annual, terrestrial, dichotomous, slender ascending herb growing up to 50 cm. Oldenlandia corymbosa is an annual, terrestrial, dichotomous, slender ascending. Sivarajan are related and have been variously circumscribed. The chinese name for oldenlandia corymbosa is shui xian cao. Media in category hedyotisthe following 4 files are in this category, out of 4 total. Distribution of asperuloside and scandosidmethylesther in leaf, stem, fruit and root of hedyotis corymbosa l. Some publications still used the synonym, hedyotis corymbosa, instead of the accepted botanical name oldenlandia corymbosa.
Antioxidant activity and anticarcinogenic properties of. Hedyotis herbacea herb uses, benefits, cures, side effects. Hc, two closely related species of the same genus, are both used for health benefits and disease prevention in china. In the present study, invivo hepatoprotective effect of 50% methanolic extract of hedyotis corymbosa hce, 100 and 200 mgkg body weight was evaluated using experimental models dgalactosamine dgaln 200 mgkg, body weight i. Clarification of the phenotypic characteristics and anti. According to trypan blue exclusion assay and western blot analysis, h. Free radicals including reactive oxygen species ros induce oxidative damage to biomolecules and have been implicated with variety of chronic diseases including cancer, diabetes, atherosclerosis. This page was last edited on 15 january 2017, at 10. All structured data from the file and property namespaces is available under the creative commons cc0 license. Pictures of the plant shown in some website peddling its medicinal value can be quite confusing between these 2 species.
Rubiaceae is a weedy herb, widely distributed throughout india. The taxonomy of hedyotis is further complicated by nomenclatural issues, in particular the designation of the type species. Here, these species are circumscribed generally, though not completely, following sivarajan and biju loc. Hedyotis ponapensis valeton hedyotis subordinate taxa. It is commonly known as parppatakapullu in traditional medicine of kerala. Leaves linear or lanceolate, acute, narrowed at the sessile base, 121 by. Hedyotis corymbosa is a common annual plant known to treat fever, diseases of liver, skin ailments and urinary infections. Names of hedyotis herbacea in various languages of the world are also given. Its common names include christmasvine, christmaspops, and snakeplant.
In the traditional medicine, over 20 hedyotis species have been used for treatment of diseases and healing practices. How hedyotis herbacea is effective for various diseases is listed in repertory format. List of various diseases cured by hedyotis herbacea. Ipomoea corymbosa is a species of morning glory, native throughout latin america from mexico as far south as peru and widely naturalised elsewhere.
Hedyotis corymbosa is extensively used in modern chinese practice for the treatment of viral infections, cancer, syndromes involving toxic heat, acne. Oldenlandia corymbo journal of international academic. It has long been used traditionally as an antiinflammatory diuretics, antipyretic, and antitoxin and enhances phagocytosis. Plants profile for oldenlandia corymbosa flattop mille. Pdf establishing a quality control system of hedyotis. Species identification of the species was performed by the research center for biology, indonesian. Malaulasimanaso oldenlandia corymbosa flat top mile.
Hedyotis auricularia is a suberect or diffused, prostrate, branched, hairy herb, with the branches 15 to 45 centimeters long. According to kusuma and zaky 2005, the whole plant of rumput mutiara can be used as medicine. Cytotoxicity assay from fractions of hedyotis corymbosa extract against breast cancer cell line t47d. Hedyotis corymbosa, antioxidant activity, dpph, ferric reducing power, abts, nitric oxide scavenging activity. Rubiaceae is an important folk herb used to prevent and cure hepatitis and liver cancer in taiwan. Hedyotis corymbosa, phytopharmacological profile, phytochemical. Pdf hedyotis corymbosa was subjected to anatomical and micromorphological studies in order to locate and identify important. The main herb is hedyotis, which has antibacterial, antiviral, antitumor, and antiinflammatory, as well as immuneboosting actions. Isolation of an anticancer asperuloside from hedyotis corymbosa l. Hedyotis diffusa herb uses, benefits, cures, side effects. Hedyotis corymbosa is one of the most popular species, which is regarded as the active ingredients in several chinese herbal.
Molecules free fulltext discovery of the potential. Rubiaceae has been used in the indian indigenous system of medicine, ayurveda, for treatment of various health aliments. In this study, optimization of enzymeassisted extraction, purification, characterization, and its bioactivities of polysaccharides from hedyotis corymbosa hcp was investigated. Bai hua she she cao, or hedyotis is a powerful herb that in chinese herbal medicine terms relieve heat and toxicity.
Preliminary phytochemical and antioxidant activity of the whole. The present study was undertaken to evaluate the antidepressant activity of methanolic extract of whole plant of h. Hc is also indiscriminately sold as hd in the wholesale chain and food markets. Inhibition of vascular endothelial growth factor expression by chinese medicine of hedyotis diffusa willd herbal compounds. Uses, benefits, cures, side effects, nutrients in hedyotis diffusa. Enjoy unrestricted access to all content and features, including. The relative abundance value of broadleaf weeds 195. In addition, scutellaria barbata is a candidate oral drug that has shown excellent efficacy and safety in early phase clinical trials targeting advanced breast cancer 29. Hedyotis bluets, quaker ladies rubiaceae 4 images at phytoimages. Bioscience hedyotis family, rubiaceae is a genus of erect decumbent or climbing herbs.